Oh, boy. That's a difficult question.
I would say that it varies so much. The course of the disease varies so much from one individual to the other. Some people have had a 19-year-long decline, and I've known another one who had a four-year decline. It's very difficult.
As I said, there are certain checkpoints we know of that we could use. They're just reached faster in one case versus the other one. It could be 15 years or 11 years instead of two years. I just can't give you a decent answer on that.