To my knowledge, there are no medications that don't have any potential side effects. If you look at all three of the choices that we have for anti-malarials right now, you see that there is a long list of potential adverse effects from each of them. All of them have gone through the Health Canada licensure process and have met the Health Canada regulatory requirements for marketing within the country with respect to safety and effectiveness.
Evidence of meeting #39 for National Defence in the 42nd Parliament, 1st session. (The original version is on Parliament’s site, as are the minutes.) The winning word was mefloquine.
A recording is available from Parliament.