Some of my patients will actually have reactions to the carrier oils or the process by which it's been made into oil. Different companies have different carrier oils. Sometimes they're actually reacting to the carrier oil that the cannabis oil is in, not the cannabis itself.
It doesn't suppress respiration the same way an opioid does. If we were talking about opioid medications and the opioid crisis, you are not going to die from respiratory failure if you take a higher amount of cannabis. Yes, it may be disconcerting. Yes, you might be temporarily in an altered state, but it's not something that's necessarily going to be permanent unless, of course, there is an underlying predisposition to a psychotic disorder or some underlying cardiac issues. It's really where the patient is at, like I said, where their brain is at, where they are at physically, by which you decide and you can judge clinically how safe you are.
Really, it's about careful monitoring, and following up and being a true doctor.