I think when we talk about randomized control trials and second- and third-level trials that doctors have to be very aware of—and for some reason medicine doesn't realize this—and know the state of the brain that they're dealing with.
Many of my patients have not just straight PTSI; they also have multiple concussions from being near IEDs. Definitely the mefloquine means another layer of sophistication is needed in terms of regimen protocols. The more complicated the trauma to the brain, the more levels that have been traumatized, the more precise and varied the regimens need to be and the more they need to have a wide breadth.
Many of my veterans with mefloquine toxicity will use three to four grams per day, three to four grams at night, and then have three grams available of many different strains that they've come to know and learn about.
Ultimately, cannabis medicine is personalized medicine. We need a different approach for practising medicine. The old paradigms are not going to work with cannabis.