Mr. Speaker, in response to parts (a) to (c) of the question, the health and safety of Canadians are the utmost priority for Health Canada and the Public Health Agency of Canada, or PHAC. Health Canada has a rigorous scientific review system in place to ensure vaccines are safe and effective in preventing the diseases they target. Before a vaccine can be approved for sale in Canada, it undergoes an in-depth review of evidence for safety, efficacy, and quality by Health Canada. Evidence provided to Health Canada includes data from pre-clinical studies, including toxicology studies, clinical trials as well as data demonstrating that manufacturing processes ensure the consistency and quality of the vaccine. Once vaccines are authorized, Health Canada releases information about the vaccine, including summaries of the data considered by Health Canada. This includes non-clinical, clinical and other studies, as well as how the decision was made. For coronavirus disease 2019 vaccines, this information can be found on Health Canada’s website at https://covid-vaccine.canada.ca/.
COVID-19 vaccines are indicated for active immunization to prevent COVID-19 caused by SARS-CoV-2. The approval of the vaccines was based on safety and efficacy data collected in non-clinical studies and clinical trials. Clinical data for these vaccines is available on the clinical information on drugs and medical devices website at https://clinical-information.canada.ca/search/ci-rc?f%5B0%5D=drug_brand_name%3A%22COMIRNATY%20OMICRON%20XBB1.5%22#tabs-0-laurier_content-1.
Clinical trials were not designed to demonstrate that vaccines were effective in preventing the transmission of SARS-CoV-2. Once available on the market, the safety and effectiveness of the COVID-19 vaccines are continuously monitored and evaluated by Health Canada and PHAC. Vaccine manufacturers are obliged to continue to collect information about the long-term safety and effectiveness of their products. Evidence from peer-reviewed studies from domestic and international sources published in the medical literature established the effectiveness of vaccination in reducing disease transmission.
With respect to parts (d) to (f) of the question, the National Advisory Committee on Immunization, or NACI, provides PHAC with ongoing and timely medical, scientific, and public health advice relating to immunization. The health and safety of Canadians has always been a priority. Leading up to and during the height of the pandemic, officials were briefed regularly on developments in relation to COVID-19.
In 2021, early NACI guidance to PHAC and stakeholders initially emphasized uncertainty surrounding the ability of COVID-19 vaccines to prevent infection and transmission and duration of protection following vaccination, and communicated the need for ongoing monitoring. As the pandemic progressed, emerging evidence suggested some degree of prevention of infection and transmission was achievable with COVID-19 vaccination and this was reflected in NACI’s advice.
The emergence of each new variant required re-assessment of how the vaccines were performing, including against infection and transmission. The emergence of the highly transmissible Omicron variant at the end of 2021 introduced new complexities, making the prevention of infection and transmission from COVID-19 vaccination, including from booster doses, less certain. All NACI advice regarding COVID-19 vaccines is published online at https://www.canada.ca/en/public-health/services/immunization/national-advisory-committee-on-immunization-naci.html and is representative of the evidence available at the time each statement was written. In addition, starting in March 2021, summaries of NACI advice were also provided by PHAC to succinctly communicate the key points and implications of the NACI guidance to the public.
Informed consent occurs through discussion between health care providers and patients on the risks and benefits of a vaccine. In order to support these informed consent discussions, PHAC communicated the evolving evidence on vaccine effectiveness to healthcare providers throughout the COVID-19 vaccine rollout. This began in December 2020 when PHAC launched a series of webinars that communicated what was known and not yet known about the newly authorized vaccines from clinical trial data, as well as recommendations for their use. PHAC continued to deliver webinars to update health care providers as evidence emerged throughout 2021 and 2022. Additionally, as noted, NACI statements and the Canadian Immunization Guide were updated to reflect the most recent evidence on vaccine effectiveness as it emerged. PHAC's webinars for healthcare providers on COVID-19 vaccines can be found at https://canvax.ca/public-health-agency-canada-phac-vaccine-confidence-webinar-series.
With respect to part (g), the NACI secretariat was the source of messaging for all officials, supported by PHAC, as well as Health Canada in its role regulating drugs and health products to support public safety.
With respect to part (h), these messages were approved by the president of PHAC and Health Canada’s deputy minister.