Thank you very much, Mr. Chair and members of the committee, for the opportunity to testify before you today.
My name is Françoise Vanni and I lead the external relations and communications team at the Global Fund. I had the honour to testify before this committee three years ago in the context of the sixth replenishment of the Global Fund, and I'm really grateful to have this opportunity again today as we run our seventh replenishment campaign for the Global Fund.
Let me start by expressing my gratitude on behalf of the Global Fund and our partners around the world for your long-standing support and leadership in the fight against HIV, TB and malaria and in global health more broadly.
Canada is a founding donor of the Global Fund and has always been one of our strongest partners. Our fifth replenishment, hosted by Canada in 2016, was the most successful ever at the time, and Canada was our sixth-largest donor in 2019 in Lyon when we broke that record by raising $14 billion for the sixth replenishment. This was made possible by the strong, consistent support we have received from our allies in the Canadian Parliament, so thank you.
In addition, in 2020 and 2021, Canada supported the Global Fund's COVID-19 response to assist over 100 low and middle-income countries. The Global Fund is now the primary funder for all the non-vaccine components of the COVID-19 response, including tests, treatments, medical oxygen and personal protective equipment for health workers, among others.
The Global Fund recently marked our 20th anniversary, and the programs we fund have helped save over 44 million lives since our creation in 2002. Also, the combined death rate from the three diseases has been reduced by more than half in countries where the Global Fund invests. This is proof that global commitment combined with community leadership can force deadly diseases into retreat and advance the 2030 sustainable development goals.
Over the last couple of years, of course, the impact of the COVID-19 pandemic has been devastating, particularly for the most vulnerable. For the first time in the Global Fund's history, key HIV, TB and malaria programmatic results declined. Malaria deaths, for example, increased by 12%, which is about 69,000 more deaths, the vast majority of them children under five in Africa. It could have been much worse without our agile response, but it's still devastating, and even more so knowing that these diseases are preventable and treatable.
The direct cost of the war in Ukraine is another major human tragedy, and its knock-on impacts on lives and livelihoods around the world will also be severe. They include food crises, energy crises, debt crises and so on. These will, again, disproportionately affect the most vulnerable—those already most exposed to HIV, TB and malaria.
In that context, the Global Fund's seventh replenishment this year is crucial. We need to raise sufficient resources to regain lost ground and get back on track in the fight against HIV, TB and malaria towards the 2030 targets, while also building stronger systems for health that ensure countries are better prepared for future pandemics, which we know will come.
Our target for the seventh replenishment is to raise at least $18 billion. This is an almost 30% increase from the previous cycle because of the enormous setback the world has experienced over the last two years. With at least $18 billion, our technical partners, the WHO and others estimate that we would be able to save an additional 20 million lives over the next three years and avert approximately 450 million new infections across the three diseases. The stakes could not be higher. If we do not provide the resources that are necessary, then we must acknowledge that we are essentially abandoning the 2030 commitments. This would be a tragedy that would cost millions of lives and harm economies in many low- and middle-income countries.
President Biden, who is generously hosting the seventh replenishment in New York in September, has already included a $6-billion pledge commitment for the seventh replenishment in his budget. U.S. law requires that every dollar the U.S. commits must be matched by two dollars from other donors. Without a similar 30% increase from other major donors like Canada, for example, it will be difficult to raise the remaining $12 billion needed to unlock the full U.S. pledge. Therefore, we are here today to seek your help to secure a Canadian pledge commitment that meets this target as we do not want to leave money on the table.
The Global Fund has proven to be an effective and agile partner in development, as well as in times of crisis, whether by supporting low and middle-income countries in their responses to COVID-19, or by ensuring the continuity of life-saving treatment for conflict-affected populations in Ukraine—or, indeed, in many other places.
It also a powerful tool to advance human rights and gender equity, which are at the very core of our strategy. We have, for example, significantly increased our investments for adolescent girls and young women to prevent HIV in 13 priority countries where HIV burdens are highest. In these countries, the number of new infections has dropped by 41% over the past 12 years. Also, in Global Fund-supported countries, the percentage of mothers receiving treatment to prevent transmission of HIV to their babies reached 85% in 2020 compared with 44% in 2010.
By focusing on breaking down human rights or gender-related barriers to health, the Global Fund ensures that no one is left behind.
Thank you again for this opportunity today, and I would be very happy to answer all of your questions.
Thank you so much.