Good afternoon, and thank you very much for giving me the opportunity to speak today.
By way of introduction, I'll just say that I'm the president and CEO for the Centre for Drug Research and Development, which is Canada's fully integrated national drug development and commercialization centre, supported in part by the federal government through the CECR program, which is the Centres of Excellence for Commercialization and Research program out of the NCE group.
Trade agreements like the Canada-EU CETA, which this committee has been actively engaged in, and the Trans-Pacific Partnership, both offer policy-makers the opportunity to support Canadian research and innovation, and the Canadian commercialization of research, while benefiting Canadian patients and creating jobs. In order to explain the importance of this link to competitiveness and jobs, I would like to take a few moments to describe how our organization fits within the Canadian research enterprise, and the use of it as an example as to how it relates to the discussions on TPP and CETA as well.
The mandate of the Centre for Drug Research and Development, firstly, is to de-risk discoveries stemming from our publicly funded health research and transform these technologies into viable investment opportunities for the private sector, thus successfully bridging the commercialization gap between academia and industry, and translating research discoveries into new therapies for patients. In other words, we de-risk and make investable these technological assets.
Canada is among the world leaders in academic health research in terms of the scale of investment, the quality of the work, and the discovery output. This work is supported mostly through federal government funding, some provincial funding, and then matched private funding, but to a much lower level than we hope to have. But now that we have built this foundation, we risk the return on this investment being realized elsewhere. As we know, in the world of biotech, that is very much the case already. If Canada is to strive for true S and T excellence globally, we need to create an environment that includes the full innovation continuum from discovery through to commercialization, such that the industry critical mass is reached and a self-perpetuating sustainability is achieved.
This shift is not easy. Getting new drugs and other therapeutic products to market has become more difficult with greater associated costs and risks. There is, therefore, a need to support innovation by effectively de-risking new technologies and filling the gaps in the commercialization process, what we call “translation”. To address this need, CDRD was established in 2007 to provide the expertise in infrastructure needed to enable researchers from leading health research institutions to advance promising early stage discoveries forward. CDRD is the only organization in the country and the only one of a handful in the world that has a fully integrated platform. This means that we provide expertise, infrastructure, non-diluted funding, and partnerships to source, evaluate, incubate, accelerate, and commercialize innovative health technologies in virtually any therapeutic area, and stemming from any geographic region in Canada.
A year and a half ago, CDRD also established a commercial arm, the CDRD Ventures Inc., and collectively the CDRD, the enterprise, brings dedicated resources specifically to the commercialization and monetization of high-priority technology assets, which we have successfully incubated. Already this enterprise has proven to be a high-performing incubator and accelerator. In its first six years, the CDRD enterprise has successfully established a network of 40 international and national affiliated institutions. That means from UBC to McGill and Dalhousie, and some European, Japanese, and U.S. high drug-discovery output organizations.
We have built a great innovative pipeline. Over 800 technologies have been evaluated and triaged, so that 125 of those have actually moved forward into incubation. Of these, 49 advanced towards commercialization. To date, within this period, we have actually 49 technologies that are bubbling up. There are three that were out-licensed to the private sector, to biotech and pharma, one which is now advanced into clinical trials. Four new spin-off companies have also been launched.
As a specific example of the removal of barriers and creation of value, one such spin-off is a company called Sitka Biopharma, the technology of which was founded at UBC by Drs. Helen Burt and Don Brooks. The use of this technology is in treating bladder cancer, which is a particularly virulent kind of cancer and very expensive to treat for the health care system. There's been no new drug in the treatment of bladder cancer for the last 25 years, so this a very important technology. We were able to advance it, to take this program, raise $2.5 million, both securing internal and external funding. This critical early stage funding, which we call the first valley of death in our world, was bridged, the technology advanced, a CEO was hired, and a new company established, Sitka. The technology is now moving forward and will go into full clinical trials within the next few months.
Without CDRD, this technology would have not made this kind of progress and likely not seen the light of day. Why I tell you this long story about our organization and this technology is that our ability to successfully have this kind of impact, and to leverage this kind of partnership and create value in research and development becomes severely hampered when we do not have the same ability to protect our IP as our global partners do. To continue to build on our success, it is imperative that policies affecting innovation at all stages of the product development life cycle are, in fact, conducive and in sync to innovation.
The single most critical of all these policies is patent protection, as intellectual property is the primary asset of any innovative company and organization. Canada must therefore ensure that we are home to a national patent protection regime that is equally as strong, if not stronger, as those of our trading partners. Such an internationally competitive intellectual property protection regime is critical to our ability to successfully achieve the vision and mission we share with government and other stakeholders.
It is also imperative to stimulate innovation but this can't be done without the attraction of foreign direct investment to support R and D. In the case of our centre, we have been successful in building partnerships with several of the world's top biopharma companies, which have committed close to $40 million to support the development of our projects and commercialization of these technologies. Without inflow of international capital such as this, we again would have little or no ability, as a country, to successfully take our place on the international innovation stage. It is our belief that an improved IP system will stimulate further investment of this nature in Canada.
Canada aims to be among the world's innovation leaders and as such, the federal government has invested greatly in leading edge research development and training. We applaud and value federal and provincial efforts in this regard. We feel that we must do more to nurture innovation at other stages of development as we continue to lag behind in innovation globally. We are losing ground, internationally, in many metrics.
We believe that improving our IP regime is a step in the right direction and that there are a number of areas that will be assisted by these changes. The first area is that we need to do better in developing IP here in Canada and keeping it here. Indeed, a number of reports released over the last several years concur that a misalignment of policy to fund this research, only to have it commercialized elsewhere, where the environment is more conducive, is not helpful to return on investment. When it comes to R and D and its commercialization, global borders are very porous and we must, therefore, ensure that the innovations remain in Canada as long as possible so that we may add as much value as possible.
The second area we need to do better at is providing job opportunities for our graduates, especially those in science, technology, engineering, and math, or the STEM fields. The commercialization of discoveries is where those jobs come from. Training is one of the core pillars of what the Centre for Drug Research and Development does. As such we have trained over 110 science students over three and a half years with multidisciplinary industrial drug training. Of these 110 graduates, 92% have found jobs in their field in this sector. Without an environment where industry can flourish, these trainees will have no option in the future but to find jobs in other countries.
The third area in which to improve our track record is private sector investment. By way of example on how we could foster international inflow of innovation and capital, in January of last year the Centre for Drug Research and Development led the founding of a global alliance of leading drug discovery and development centres, an association of top-pier translational research organizations including MRC Technology in the U.K., Cancer Research UK, Lead Discovery Center at Max Planck in Germany, CD3 Leuven in Belgium, and Scripps Research Institute in Florida to share infrastructure and best practices and work collaboratively to support and accelerate the conversion of early stage technology into commercial investment opportunities.
Through this alliance the CDRD-CVI also has strengthened the mechanism to attract new foreign technology, innovation, and global funding through the Horizon 2020 funding as opposed to the former paradigm of made-in-Canada discoveries often leaving the country to be commercialized elsewhere. We see these types of relationships as potentially being furthered through the Trans-Pacific Partnership and other such trade agreements. We have to play a global role in a globally competitive environment.
In conclusion it is our hope that the TPP proceeds and is ultimately executed in a manner than ensures that IP in Canada enables the attraction of foreign capital for R and D, creates new Canadian companies, and is found in the most innovative and robust technologies, thus creating jobs for our brightest and best here in Canada.